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Research in the Brennan Laboratory

In this image we see a fly blood cell that has phagocytosed a bacterium. The bacterium is expressing the red fluorescent protein mCherry, which allows us to follow its degradation in the phagosome. The green glow of the blood cell comes from expression of a GFP-Rab5 fusion protein. The intense ring of green around the bacterium represents the recruitment of the Rab5 protein to the phagosome, an early transient step in phagosome maturation. Image credit: Mobina Roshandell.
